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Subjects were randomized to lixisenatide 10 mcg/d (up- or down-titrated to max 20 mcg/d) or placebo

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When you take semaglutide GLP-1, it signals your brain to feel fuller faster and reduces hunger, which naturally leads to eating fewer calories

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This highlights that there could be more potential opportunities around positive allosteric modulation of the GLP-1 receptor