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ZhangWMiaoJZhangGLiuRZhangDWanQet al
From ubiquinol, the electrons pass down the redox gradient through complex III (coenzyme Q-cytochrome c oxidoreductase) to cytochrome c , then to complex IV (cytochrome c oxidase) and to the final acceptor, oxygen (O 2 ) to produce water
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By promoting the conversion of acetyl-CoA to acetylcarnitine, carnitine reduces the ratio of acetyl-CoA/CoA, thereby reducing the activity of PDH kinase and restoring the activity of PDH, allowing more pyruvate to enter the mitochondria for oxidation to produce energy [288]
IV administration should be done by medical professionals only
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