The same result was obtained in the active controlled studies (WMD = 2.37 kg, 95% CI 0.30 to 4.44, P = 0.02, I 2 = 0%), while there is no statistically significant distinction observed between the two subgroups ( P = 0.55) (Additional file 2: Fig
Pending those results, some authors in the literature have advocated for early prophylactic intervention for levels of retinopathy that approach current evidence-based treatment thresholds
Weight loss takes time, and while semaglutide can help, it is not a quick fix
Patients should not expect dramatic weight loss in the first week , and healthcare professionals typically assess treatment response over a period of months rather than days
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