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Some studies point to the ability of serine, a nonessential amino acid, to boost glutathione production, potentially through increased cysteine availability and a decrease of hypermethylation

Because glutathione has a relatively short halflife (on the order of minutes in circulation) and oral glutathione is broken down in the gut and at cell surfaces, IV delivery is often used to bypass these absorption limitations and achieve higher shortterm plasma levels

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for the treatment of type 2 diabetes mellitus (under the brand names Ozempic for injection and Rybelsus for oral tablets) and chronic weight management (as Wegovy)

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Blum, are going beyond the scale and leaning more heavily into the potential healthspan and longevity benefits

Review article: Pharmacologic management of obesity - updates on approved medications, indications and risks