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Costs of treating diabetes-related complications were based on previously published studies (Supplementary Material, Table S3) [37,38,39,40,41]

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This 1:2 stoichiometry of HGF binding to c-MET is consistent with previous c-MET-HGF binding assays that indicated the coexistence of multiple c-MET binding sites at HGF 13

When combined, the body appears to sustain higher NAD+ levels for longer and enhance the utilization of NAD+ within cells

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