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Looking forward, the field is moving toward precision medicine
In October 2023, the FDA cleared the use of Bimzelx for adult patients with moderate-to-severe plaque psoriasis and in September 2024 expanded its label to include psoriatic arthritis, ankylosing sspondylitis and non-radiographic axial spondyloarthritis
GLP-1s work in multiple ways in the body including slowing down the digestion of food and release of glucose into the bloodstream, increasing insulin secretion in response to a meal, and regulating appetite control signals in the brain
Signs of an allergic reaction, though rare, constitute a medical emergency
Feeds mitochondrial threonine dehydrogenase pathway, generating succinylCoA and ATP, combating fatiguerelated low mood
The separate AUD and SUD analyses suggest GLP-1RAs may be particularly effective for chronic AUD outcomes, guiding targeted use in practice
