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These data indicate that further investigation into JS-K as an alternative chemotherapeutic agent is much needed

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This process is known as macrocyclization

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The mobile phase consisted of 15mM ammonium bicarbonate supplemented with 2.5 M medronic acid in LC-MS grade water (mobile phaseA) and 15mM ammonium bicarbonate containing 2.5 M medronic acid in LC-MS grade 90% (v/v

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