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10.1016/0014-5793(94)01430-9 FEBS Lett
Deth, and H
Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019
This GLP-1R plus strategy, combining GLP-1 RAs with other hormone-based medications that target different pathways, such as amylin or GIP, may result in additive or synergistic effects that enhance weight loss and improve metabolic outcomes
Ferroptosis is a novel iron-dependent mode of cell death distinct from apoptosis and necrosis and is characterized by lipid peroxidation [3], a process that generates large amounts of Fe 2+ , lipid hydroperoxides (LOOH), and ROS, and is accompanied by a decrease in the activity of glutathione peroxidase 4 (GPX4) or glutathione (GSH) depletion
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