43,76 The results of the 52-week MAESTRO-NAFLD-1 trial supported the efficacy and safety of resmetirom at doses of 80 mg and 100 mg qd (NCT04197479), which are being applied in the ongoing phase 3 MASH study, MAESTRO-NASH
The condition is serious, but despite an apparent increased incidence among patients taking GLP-1s, the condition is still uncommon
Mechanisms of podocyte injury and implications for diabetic nephropathy
Hepatocyte growth factor as mitogen, motogen and morphogen, and its roles in organ regeneration
Not suitable for individuals with a history of lung diseases or respiratory disorders
In murine models of bleomycin-induced lung injury, genetic deletion of the GLP-1 receptor was associated with reduced inflammatory injury, and pharmacological GLP-1 receptor activation exacerbated pulmonary inflammation [71]