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Rapid kill of malaria parasites by artemisinin and semi-synthetic endoperoxides involves ROS-dependent depolarization of the membrane potential

Ultimately, this strategy completes the full chain of precision research from drug screening to mechanism validation by integrating organoid functional experiments with multi-omics molecular maps (Mao et al., 2024)

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These adverse events primarily included mild to moderate gastrointestinal disorders, with no severe hypoglycemia and a safety profile consistent with the GLP-1 receptor agonist class

Integration of hepatic drug transporters and phase II metabolizing enzymes: mechanisms of hepatic excretion of sulfate, glucuronide, and glutathione metabolites

Meyer DJ, Coles B, Pemble SE, Gilmore KS, Fraser GM, Ketterer B