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However, the translation to clinical efficacy in human osteoarthritis remains ambiguous, as weight loss appears to play a substantial role in pain alleviation [21, 22]

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Berberine activates AMP-activated protein kinase (AMPK), a cellular regulator that supports glucose uptake, improves insulin sensitivity, and influences fat metabolism

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After 24 hours, warm compresses or gentle massage can improve blood resorption

NCT04216589), a phase IIb trial to evaluate the effects of semaglutide on liver fat content in people with HIV