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Similarly, although hepatic dysfunction can occur with large niacin doses (1-3 grams daily over months) causing elevated liver enzymes or jaundice, niacinamide at 100 mg is very unlikely to have any adverse effect on the liver

Therapies are prescribed and/or recommended following a clinical evaluation of your labs and health history, where appropriate

So, regardless of how much (or how little) you have to take daily, there are solutions available for you

However, this dosing is from animal studies and has not been validated for human use