Inclusion Criteria Exclusion Criteria Timeline for a Trial Participant Screening Participants are screened for eligibility to participate in the trial Treatment Participants receive once-weekly subcutaneous injections of CagriSema or placebo for up to 40 weeks, with dose escalation periods for active comparators Follow-up Participants are monitored for safety and effectiveness after treatment What Are the Treatments Tested in This Trial
Both are once-weekly amylin receptor agonists, but eloralintide is selective for the amylin receptor while cagrilintide also activates the calcitonin receptor, making it a dual amylin and calcitonin receptor agonist
Tan et al., 2016
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