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This hypothesis was supported by luminescence activity data, which showed that all profiled variants had activity on both GD_SS1.1 and GD_SS1.2, regardless of their evolutionary trajectory (Extended Data Fig
Consequently, chronic alcohol intake is believed to impede the autophagy process in hepatocytes, exacerbating liver cell damage (Salete-Granado et al., 2023
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Studies have shown that p53 can induce ferroptosis by inhibiting SLC7A11 transcription and upregulating ALOX15 [71, 72]
Kim H, Seo S, Chang J, et al
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