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In addition, we did not conduct metabolite analysis in tissues, especially in target organs, owing to the small sample size

G-Omeprazole 40 mg/vial substantially reduces the antiplatelet activity of Clopidogrel through competitive inhibition of CYP2C19, potentially increasing the risk of cardiovascular events in patients who depend on Clopidogrel for cardiovascular protection (e.g., post-cardiac stenting)

This is often easier when the primary goal is consistency

Animal-to-human amount translation is not straightforward and requires allometric scaling, and human pharmacokinetics, safety, and efficacy remain uncharacterized in published literature

The Lancet (2021) 4

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