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Conclusion The use of GLP-1 receptor agonists in the treatment of addiction is a promising area of research with the potential to offer new, effective solutions for managing substance use disorders

Singh M, Jadeja SD, Vaishnav J, Mansuri MS, Shah C, Mayatra JM, et al

Still outstanding are TRIUMPH-5 (head-to-head vs tirzepatide), TRIUMPH-6 (weight maintenance), the MASH readouts, and the multi-year TRIUMPH-Outcomes trial

Because the majority of the -cells do not express GLP-1R, and also because GLP-1 inhibits glucagon secretion even in T1D patients with low insulin pancreatic reserve, the mechanism by which GLP-1 decreases glucagon secretion is still a matter of debate [15]

His first experiments did not go as planned