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Slower titration equals better tolerance
CO 2 Laser-Resurfaced Skin Miller et al., Archives of Facial Plastic Surgery (2006) Miller and colleagues evaluated the effect of topical copper-tripeptide complex on wound healing following carbon-dioxide laser facial resurfacing a procedure that creates a controlled superficial burn requiring extended recovery and characterized by prolonged post-treatment erythema
Both are dominated by gastrointestinal adverse events nausea, constipation, diarrhea, vomiting that are mostly mild-to-moderate and dose-related
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The stability of the BBB largely depends on its vascular integrity and selective permeability
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