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That is difficult clinically
The included dietitian access and flat-rate pricing model add genuine value that partially offsets the mid-range price point
J Thromb Thrombolysis 33:143153
Currently, medications for obesity alone are not covered under Medicare
As the first anti-obesity drug targeting multiple receptors, tirzepatide (Zepbound, Eli Lilly), a dual GIPR/GLP-1R agonist, was approved by the FDA in 2022
Clinical Significance If approved, orforglipron would be the first oral medication specifically approved for chronic weight management that activates the GLP-1 receptor without requiring injection, absorption enhancers, or dietary restrictions
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