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These findings suggest that CB-839 may induce alternative mechanisms of mitochondrial SOX accumulation

If the agency formally removes GLP-1 drugs from its shortage list, the regulatory pathway that has fueled the companys rapid expansion into the weight loss space to this point will become less straightforward, forcing a reckoning with its business model and strategy

glucose tolerance test (IPGTT) or plasma glucose during ad libitum (AL) feeding (Extended Data Fig

In the 12mg cohort, 83% of participants achieved at least 15% weight loss, and more than half exceeded 25%

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