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SGLT2-i lower SBP by an average of ~2.5-4.0 mmHg and DBP by 1.5-2.0 mmHg

Furthermore, it has been established that the minerals and bioactive compounds in plant-based diets, such as vitamins C and E, beta-carotene, and polyphenols, exhibit antioxidant properties associated with reduced CVD and MetS (228, 229)

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The practical protocol approach for most researchers starts at a lower dose, typically 2mg weekly, and escalates every three to four weeks based on tolerance

In addition to binding zinc, TdfH has been shown to bind calprotectin and deliver zinc into the neisserial cell (Jean et al., 2016), and was therefore renamed CbpA, for calprotectin-binding protein A (Stork et al., 2013)

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