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The agency gave the company a voucher for a priority review and a decision could come early this year.

New England Journal of Medicine, 384 (11), 9891002

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MarketScan contains claims information provided by a sample of large employer plans, made representative of the ESI market by using weights to match counts in the Current Population Survey for enrollees at firms of 1,000 or more workers, adjusting by sex, age, and state

2008 Jan;18(1):17-26

Also, 500 mcg is pretty low, and since the half-life is short, it really should be dosed twice a day