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Continued over-stimulation of pancreatic -cells by whey protein-driven IIS after the post-weaning period may continuously diminish nuclear FoxO levels, thereby promoting oxidative stress damage of -cells finally resulting in early onset of -cell cellular senescence and apoptosis [26]
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In brief, a list of lesions was compiled for each mouse that included both neoplastic and non-neoplastic diseases
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Reconstitute before use per laboratory protocol
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