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Common, mild effects: Temporary soreness, redness, or irritation at the injection site
B12 injections for fatigue and energy Correcting a B12 deficiency frequently resolves fatigue, since B12 is essential to red blood cell production and neurological function
Because there are so few human studies, we do not have a clear picture of long-term safety
Most side effects from B12 shots resolve quickly, making them generally well-tolerated for routine supplementation
Thuesen, B
The NHS treatment pathway and the 2024 NICE guideline both assume B12 injections are given in a clinical setting against a confirmed deficiency, not self-sourced and self-administered
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