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Metformin, through the induction of 5' AMP-activated protein kinase and subsequently insulin sensitivity, has been widely used as a therapeutic agent in various conditions, including type 2 diabetes mellitus, PCOS and gestational diabetes (Reference Rice, Elia and Jawad42)
The medicine can lower your risk of developing type 2 diabetes when diet and lifestyle changes arent enough, says Rachel Pessah-Pollack, MD, an endocrinologist and clinical professor of medicine at NYU Langone Health
doi:10.1016/j.peptides.2005.01.029
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Key risk factors include: History of Gallstones: These can obstruct the pancreatic duct, leading to inflammation
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