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We also observed an increase in the 18 kDa translocator protein TSPO, which is a mitochondrial cholesterol-binding protein and upregulated in microglia during inflammatory activation associated with neurodegeneration (Fig
Molecules 19(10):1692516936
Schrodt C, et al
M.DobbsR
BPC-157 is a synthetic 15-residue peptide with the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Oxidative stress results in damaging the nucleic acid and protein and lipid peroxidation, thereby altering the carbohydrate metabolism and thus leading to cellular death and its dysfunction
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