American Society of Health-System Pharmacists
In addition, IDH1-dependent reductive glutamine metabolism produces NADPH, which decreases mitochondrial ROS during anchorage-independent growth 64
*Chuncho Macaw Clay Lick
Metabolomic results confirmed systemic glutathione depletion and mitochondrial dysfunction, as evidenced by reduced levels of S-lactoylglutathione, carnitine species, and NAD+ intermediates
doi:10.1038/35043073
Acknowledgements Grammarly (Superhuman Platform Inc., San Francisco, CA, USA) was used to assist with proofreading and language editing of the manuscript, and Google Gemini (Google LLC, Mountain View, CA, USA) was used to assist with figure creation