Much of the field is now being built on multi-mechanism approaches: tirzepatide combining GLP-1 and GIP, retatrutide adding glucagon to that mix, and cagrilintide plus semaglutide taking yet another route to polyagonism
It typically settles over time and can be improved with micro-needling
Heres a quick guide on who might benefit most from each medication: Choose Zepbound if: You want a contemporary drug for obesity with an impact on appetite, which had a positive result on glycemic control and you never had pancreatitis or thyroid cancer
Focus on non-scale victories: Look for improvements in energy, mood, and life quality not just weight
Tendon pain may be related to overuse, poor loading mechanics, inflammation, partial tearing, inadequate recovery, metabolic health, medication exposure, or age-related tissue changes