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The medication occupies GLP-1 receptors to suppress appetite, manage blood sugar levels, and promote weight loss
Appetite typically begins to return within one to two weeks after stopping tirzepatide, though the timing varies
But she added: We have concerns over the length of time it might take for people to gain access. Dr Kath McCullough, NHS Englands national specialty adviser for obesity, said weight-loss drugs were an important tool to help tackle one of the greatest public health issues facing the NHS
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However, newer medications target multiple metabolic hormones: GLP-1 drugs (single-hormone): semaglutide medications like Wegovy and Ozempic Dual-agonist drugs: tirzepatide medications like Mounjaro and Zepbound (target GLP-1 and GIP receptors) Triple-agonist drugs: retatrutide (targets GLP-1, GIP and glucagon receptors) Researchers believe stimulating multiple hormone pathways may produce stronger effects on appetite, metabolism and energy expenditure
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