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Heikes KE, Eddy DM, Arondekar B, Schlessinger L
In order to further address the different glucose-lowering effects of GLP-1RAs, we divided the studies into normal BMI, overweight BMI, and obese BMI groups in our meta-analysis
Critical adjustment period Early months require guidance for dosing, tolerance, & progress for long-term success 2x Longer on therapy Ongoing support keeps patients on GLP-1s 2x longer, maximizing long-term benefits 9+ Systems affected GLP-1s influence brain, heart, kidney, & more
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Stop taking this medicine and call your doctor right away if you become pregnant
intramuscular administration Subcutaneous (into fatty tissue of abdomen, typically 1-2 inches lateral to navel, using a 25-27 gauge, 5/8-inch needle): 28% report injection-site soreness Easier for self-administration Slower absorption (peak serum B12 at 12-18 hours vs
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