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Compared to cytosolic NADK (cNADK), mitochondrial NADK (mNADK) has a distinctive feature that it can directly phosphorylate nicotinamide adenine dinucleotide (NADH) to generate NADPH to alleviate oxidative stress in mitochondria

Pharmacological restriction of cellular NADPH availability by targeting its synthesis pathways to impair NADPH homeostasis is currently recognized as a crucial and potential strategy for cancer treatment

doi:10.1016/S1569-1993(03)00097-3

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Throughout each issue, there are scientific study results relevant to that months chosen topic (like sleep, dopamine levels, body fat, and so on)