For many patients, appetite signaling returns and weight regain is common after stopping
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GSTs exhibit glutathione peroxidase activity and catalyze the reduction of organic hydroperoxides to their corresponding alcohols
Glutathione is naturally produced by the body and is also well-tolerated, though some people may experience mild nausea if taken on an empty stomach
The acetyl group attached to the sulfur atom of the cysteine residue in S-acetyl L-glutathione helps protect the molecule from oxidation and enzymatic breakdown, allowing it to pass through the digestive system more intact
Hyperphagia is the excessive sense of hunger leading to overeating, which can cause severe obesity and related health issues in PWS patients