Here we show that oral administration of the non-calorie sweetener, rare sugar d-allulose (d-psicose), induces GLP-1 release, activates vagal afferent signaling, reduces food intake and promotes glucose tolerance in healthy and obese-diabetic animal models
M.MukhiD.Andrade-SilvaM.LiuH.GuanY.et al (2025)
Study: Glucagon-like peptide 1 receptor agonist discontinuation and risks of major adverse cardiovascular events in adults with type 2 diabetes: target trial emulation
These effects include neurotrophic, neurogenic, neuroprotective, anti-inflammatory, and insulin sensitizing actions, a field currently under intensive investigation and not yet fully understood
Primary antibodies (Table S1) diluted in TN buffer (0.1 M TrisHCl, 0.15 M NaCl, pH 7.5) were reacted overnight at 4 C
Metabolism 59 , 206214 (2010)