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When insulin sensitivity improved through exercise or bariatric surgery, NNMT levels in adipose tissue fell suggesting NNMT activity tracks with metabolic state rather than being a passive marker
10.1016/s0928-4257(99)00123-0 129 SkorjanecS.DolovskiZ.KocmanI.BrcicL.Blagaic BobanA.BateljaL.et al (2009)
Nrf2 Pathway Activation Glutathione depletion triggers activation of Nrf2 (nuclear factor erythroid 2-related factor 2), the master transcription factor for antioxidant gene expression
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