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The consequences extend beyond simple fatigue: B12 deficiency can trigger mood disturbances, cognitive decline, nerve damage, and compromised immune function

All of these findings are in rodents, and their relevance to humans is unestablished

Structural tissue remodeling continues through weeks eight to twelve, with objective imaging improvements typically visible at the eight-week mark when applicable

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The use of hydroxocobalamin became first line due to its low adverse risk profile, rapid onset of action, and ease of use in the prehospital setting

Cardiovascular Health: Maintaining proper levels of B vitamins, particularly B6 and B3, can promote heart health and reduce the risk of cardiovascular diseases