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No one should take it without medical supervision and a clear clinical reason

When Medicare GLP-1 coverage applies outside the Bridge Program This is the part most patients do not realize

Special situations: blood work considerations Blood work during pregnancy Semaglutide is contraindicated in pregnancy and should be discontinued at least 2 months before a planned pregnancy (given its 7-day half-life, approximately 5 weeks of clearance time is recommended)

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For weight management without diabetes, the role of metformin is less established and stopping it may be appropriate if tirzepatide alone is achieving your goals