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If tolerance to the satiation effect develops while the dose-limiting nausea does not, the benefitrisk ratio of a given weekly dose would drift over time and a titration schedule built on early-weeks tolerability would be calibrated to the wrong period

This investigation found no correlation between plasma cysteine and nutritional status, pointing to impairment of trans-sulfuration as the major cause

Furthermore, the NAC group reported marked, subjective improvements in shortness of breath (dyspnea), severe fatigue, and brain fog

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10 , e12465 (2024)

The BCO1 gene is located on chromosome 16q23.2 and is composed of 11 exons that encode a 547 amino acid protein