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2023), exert neuroprotective effects by upregulating antioxidant enzymes (Devasagayam et al

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In vitro, the HER2xAPLP2 BsADC with a DAR of 4 exhibited potent cytotoxicity against HER2-positive cells (e.g., IC 50 of 0.8 nM in BT-474), significantly outperforming a conventional HER2-targeting ADC

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Suppression of the malignant phenotype in pancreatic cancer by overexpression of phospholipid hydroperoxide glutathione peroxidase