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Less common but important things to know: gallstones can develop with rapid weight loss and we monitor for symptoms

Last reviewed: June 22, 2026 Last updated: June 22, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Our dedicated team of healthcare professionals will guide you through personalized treatment plans, ensuring your weight loss goals are met with utmost care and support

Hypoglycemia In the above studies (N=9), adverse reactions of hypoglycemia were based on all reports of symptomatic hypoglycemia

Obesity weight is a complex problem

Certain medicines including corticosteroids, some antidepressants (such as mirtazapine), and antipsychotics are associated with weight gain and may partially offset the benefits of retatrutide (BNF