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Conclusions : Lower plasma concentrations of glutathione suggest lower intracellular concentrations of the tripeptide

This approach is very useful for evaluating the effects of long-term drug exposure

Heart rate: Increases in resting heart rate have been observed with incretin-based agents

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The so-called incretin effect describes this phenomenon and also explains that orally ingested glucose leads to a higher insulin response than intravenously administered glucose leading to isoglycemic glucose excursions compared to oral glucose ( There are, however, challenges and limitations regarding therapy with GLP-1RA