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In follow-up from the STEP 1 trial on semaglutide, average weight loss on semaglutide was 17.3% at week 68

A substance which initiates a physiological response when combined with a receptor

Notably, SCFAs act as critical signaling metabolites that activate G-proteincoupled receptors (GPCRs), thereby suppressing pro-inflammatory cytokine production and promoting regulatory T-cell expansion within the colonic mucosa (301)

Average weight loss was 13 pounds

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