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Type 2 diabetes represents approximately 90%-95% of diagnosed diabetes cases (2026, United States), concentrating commercial opportunity in the population covered by Ozempic's core indication
Walsh 2005)
A comprehensive literature search was conducted between January 1998 and May 2025 using PubMed/MEDLINE, Scopus, Cochrane CENTRAL, Clinicaltrials.gov, regulatory sources (EMA, FDA), and manual searches of high-impact journals ( NEJM , Lancet , JAMA , Diabetes Care , Obesity , Nature Medicine , Cell Metabolism )
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In comparison, patients who used retatrutide (8 mg and 12 mg once weekly) lost 17.5% at 24 weeks and 24.2% of their body weight after 48 weeks in phase 2 clinical trials
Eur Cells Mater
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