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Puede modular la sealizacin del sistema nervioso central, incluidas las vas de dopamina y glutamato, en modelos de lesin cerebral en roedores

The relationship between B12 and mental health is well established in medical literature, though it is primarily characterised by the psychiatric consequences of deficiency rather than excess

It is almost always fatal

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ERR target-gene expression (for example, Ppargc1a, Tfam, OXPHOS subunits), oxygen-consumption rate in cells, and, in vivo, indirect calorimetry parameters (energy expenditure, RER), plus mitochondrial DNA and cytochrome-c content in muscle

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