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It is also worth noting that in obese patients with T2DM, GLP-1RA-mediated weight reduction has been associated with the detection rate of breast cancer [34], with the highest incidence observed in patients who experienced more than 10% weight loss following treatment [35]
The doses studied in clinical trials range from 1mg to 12mg, with 12mg being the highest dose tested and producing the greatest weight loss (-24.2% at 48 weeks in Phase 2, -28.7% at 68 weeks in Phase 3)
doi: 10.1016/j.bbrc.2021.06.036 85 YanXLiuYLiCMaoXXuTHuZet al
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