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A meta-analysis of 26 RCTs (n=3,864) found that NAC (typically 600 mg twice daily) reduced the incidence of contrast-induced nephropathy by 40% (OR 0.60, 95% CI 0.44-0.81) (Gonzales et al., BMC Med, 2007) [67]
In addition, the number of mitochondria increase from primary spermatocytes to round spermatids, a process that requires iron for mitochondrial ironsulfur clusters and heme synthesis
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