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Originally developed for type 2 diabetes management, higher-dose formulations (Wegovy) received FDA approval for chronic weight management in 2021
A retrospective observational study published in Clinical Nutrition found that nutritional deficiencies were diagnosed in 12.7% of patients within 6 months of starting GLP-1 receptor agonists, and that number climbed to 22.4% within 12 months
However, if someone has ongoing inflammation or signs of infection, they should seek prompt medical attention
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GLP-1 and GLP-2 significantly modify feeding behaviour
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High cortisol (the primary stress hormone) is directly catabolic to muscle tissue and can suppress testicular function
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