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Furthermore, a clinical trial involving 39 healthy adults who consumed roselle beverages rich in polyphenols and PCs reported significant increases in the serum levels of SOD and GSH-Px and reduced GSH-Rd, following the daily intake of 200 mL of the beverages (containing 3.92 g of gallic acid and 3.3 g anthocyanins of cyanidin-3-glucoside) for six months

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IGF-1 is necessary as well as sufficient in muscle growth (anabolic) and has been shown to also be highly anti-catabolic agent as well