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For most patients, a weekly B12 shot for the first four weeks rebuilds depleted B12 levels, followed by maintenance shots every two to four weeks

The first Phase 3 trial, TRIUMPH-4, reported 28.7% mean body weight loss at 12mg over 68 weeks, per Lillys published trial data, the highest figure reported for any obesity drug in a Phase 3 setting

Safety Research Priorities Comprehensive long-term safety studies are critically needed, particularly given concerns about potential effects on cancer development and progression

Will I regain the weight if I stop the medication

That means incorporating nutritional decisions, meal planning, and physical activity to keep the weight off

Psychiatry 6 , e951 (2016)