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Phase 1: Establish tirzepatide baseline (weeks 1-4) Start tirzepatide alone at 2.5mg weekly
A., Adelhorst, K., Pedersen, B., Kirk, O
As expected, the drugs affected regions already associated with appetite regulation
Park SB, Jung WH, Kim KY, Koh B (2020) Toxicity assessment of SiO 2 and TiO 2 in normal colon cells, in vivo models and human colon organoids
In particular, the drugs can boost insulin sensitivity (in part by slowing the passage of food in the GI tract) and act on parts of the brain that influence appetite and cravings, all of which can reduce that never-quite-full feeling common in folks with PCOS
