This involvement in nucleotide synthesis contributes to the maintenance of genetic material in nerve cells (6).Additionally, PLP plays a role in homocysteine metabolism, catalyzing the reaction that forms 5,10-methylene-THF, needed for the methylation of homocysteine to methionine,which also depends upon B2, B6, B9 and B12 vitamins (6, 11, 57, 58) ( Figure 5 )
A vitamin B12 deficiency occurs when your body does not have enough healthy red blood cells
This is the formation of new blood vessels
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Mild GI discomfort (nausea, bloating) is occasionally reported, particularly at higher doses [1][29]
Regulating the profibrogenic cytokine TGF-, which is found to be elevated in fibrotic Autoimmune diseases such as systemic sclerosis