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Increased cAMP levels act as a secondary messenger, signaling the cell to produce and release growth hormone

No serious side effects were observed in many clinical trials

The mechanism involves upregulation of tissue inhibitors of metalloproteinases (TIMPs) and simultaneous downregulation of matrix metalloproteinases (MMPs), shifting the extracellular matrix balance toward net deposition rather than degradation

This shift in energy use is particularly beneficial during weight loss or calorie deficits, where muscle loss is a common concern